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CCSVI Treatment Aftercare

 

Related Documents:
Endothelial Health
CCSVI Treatment and Efficacy
CCSVI Treatment Risks
1.  Overview
2.  Immediate Aftercare - Medical Monitoring
3.  Aftercare Begins Prior to Treatment (Blood Clotting and Blood Thinners)
4.  Beyond Drug Monitoring:  Longer-term Vascular Health

 

 

 

 

Aftercare Quick Facts

Physicians often focus only on the short-term CCSVI treatment aftercare that is critical to your immediate physical health. This typically includes the following:

  • Monitoring the effects of prescribed drugs
  • Monitoring/reporting unexpected physical changes

Ideal longer-term aftercare may actually begin before treatment, with pre-procedure blood coagulation testing which may guide your post-procedure medication regimen

Longer-term aftercare can focus both on any medically necessary monitoring AND on overall vascular and whole-body health

Patients and physicicans can work together to craft an individual longer-term aftercare plan.  Research suggests that such a program could include:

  • Pre-procedure blood coagulation testing (to identify potential risks prior to treatment)
  • Rigorous drug monitoring
  • Monitoring/reporting unexpected physical changes
  • Proper hydration
  • Physical activity (but not overexertion)
  • Sufficient rest
  • Following sound endothelial health practices:
    • Not smoking, and drinking only in moderation
    • Reducing stress
    • Promoting healthy liver function
    • Sufficient vitamin D intake
    • Encouraging levity, laughter, and emotional well-being
    • Following common-sense nutrition
    • Increasing your intake of healthy fats and proteins
    • Taking probiotics
    • Ensuring proper intake of essential minerals (e.g., magnesium, zinc, calcium)
    • Using antithrombotic and anti-inflammatory herbs

 

 

1. Overview

As more people with CCSVI are being treated with angioplasty, increasing numbers are asking about both short and long-term aftercare.

While short-term aftercare typically focuses on monitoring the effects of any medications prescribed after treatment, and any unexpected physical changes/discomforts, there is no universally recommended longer-term aftercare. In fact, physicians often hesitate to recommend long-term aftercare because such programs have not been formally defined or tested.

However, many physicians are willing to work with patients to help develop reasonable longer-term aftercare that emphasizes both vascular and whole-body health. The goal of CCSVI Alliance's Aftercare page is to provide a menu of research-based aftercare activities from which a patient, together with their medical professional, may craft an individualized, common-sense plan that emphasizes both short-term medical monitoring and longer-term vascular and whole-body health.

2. Immediate Aftercare – Medical Monitoring

Following angioplasty, physicians typically focus on monitoring the patient's immediate physical health. Physicians generally believe there is a "risk window" for patients that is highest during the procedure and in the first few hours after treatment, but that quickly decreases over the next several weeks to a month or two. Thus, to many physicians, aftercare consists exclusively of critical medical monitoring during this risk period. Typical risk-based aftercare programs include:

    Beyond these critical activities, many physicians don't recommend any long term post-procedure care other than generalities about smoking and excessive drinking (and other behaviors that are obviously bad for your health). However, patients often wish to understand various general risks to their vascular system, and steps they can take to achieve optimal vascular health following CCSVI treatment.

    In fact, research suggests that patients can take a number of steps to maintain or strengthen their vascular health. Further, research has tied many of these steps to improved overall physical health, and in some cases, to reduced risks associated with MS. However, before considering a long-term vascular health program, patients must know that, at this time, no research has been conducted showing that any activity or program will prolong the effectiveness of CCSVI treatment or reduce the risk of restenosis.

    3. Aftercare Begins Prior to Treatment (Knowing your Blood Coagulation factor; Planning your Aftercare)

    While several studies have confirmed the general safety of CCSVI treatment1,2, excessive blood clotting (or its opposite: excessive bleeding or bruising) is a legitimate risk for several weeks to a month or two after angioplasty. Thus, a good aftercare program begins with understanding and managing your blood clot risk prior to treatment.

    Many factors may contribute to the risk of clotting or bleeding. These include:

    • Characteristics of the vein(s) and obstructions being treated

    • The type of treatment (for example whether stents or balloons or both are being used)

    The patient's natural propensity for clotting

    Fortunately, your natural propensity for clotting (known as your "clotting factor," or "coagulation factor") can be tested prior to treatment. Knowing your clotting factor can be extremely helpful to your aftercare program because it allows your physician to better tailor your post-procedure medication(s), dosages, and timelines based on your individual clotting risks.

    While the risk of clotting due to angioplasty is low, your personal coagulation factor may increase post-procedure clotting risks:

     

     

    The risk of excessive clotting or bleeding ranges from relatively negligible to, in extreme cases, issues that could be life-threatening if not properly monitored and treated. If you have a coagulation disorder, its best to know it and plan for it prior to treatment.

    Managing Blood Clotting after Treatment

    Traditionally, two classes of drugs are used to manage clotting:

    • Anticoagulants 
    • Antiplatelets

    While both of these medications are sometimes referred to as "blood thinners," they are really anti-clotting medications, and they work differently to prevent clotting.

    Anticoagulants, which include commonly prescribed post-CCSVI treatment drugs like Warfarin, Coumadin, and Heperin, work by inhibiting blood clot formation.

    When you are on an anticoagulant, you need regular blood checks to monitor your PT time/INR. There is a specific "zone" of anticoagulation your doctor will want you to remain in for several weeks up to two months after your procedure. PT Time/INR is a simple blood test that can be done in a GP's office once a week or so.  

    Furthermore, many doctors are now prescribing Pradaxa, which is an anti-coagulant, but does not require regular INR testing.

    Antiplatelets, which include aspirin and plavix, help stop platelets from adhering to an area of the vessel wall after it has been irritated or injured during ballooning or stent placement. Platelets are naturally occurring "sticky" cell particles that move freely in your blood where they can adhere to any damaged area in the vessel wall. These sticky platelets clump together to begin the clotting process. Too many platelets, however, can spur development of unwanted clots, and too few may increase bruising and bleeding.

    Generally, antiplatelets are considered less risky than anticoagulants, and their use does not require weekly blood checks. Nonetheless, there can be side effects such as bruising and excessive bleeding. Because antiplatelets work differently from antigoagulants, they are not a replacement for anticoagulants. Some doctors prescribe both, others one or the other. Talk to your doctor. Ask them why they use a particular method.

    Additional details about anticoagulants, including drug names, risks, and drug interactions, is available here.

    A nice overview of coagulation and clotting in clear language is available here.

    To determine whether you have uncommonly high or low blood coagulation factors, you may request that your physician have your blood coagulation factor tested prior to treatment. One of several tests is commonly used:

    An explanation of what these tests mean and how they work can be found here: PT & INR and D-dimer.

    ⇒ Patient Tip: Don't assume your doctor will automatically request a coagulation test prior to treatment. Ask him/her!

    Beyond requesting a test for your blood coagulation factor, it's best to work with your physician on your aftercare plan prior to treatment. Some basics that you may want to ask your doctor:

    Note that because everyone's treatment is unique, your immediate aftercare program may also be unique.

    4. Beyond Medical Monitoring: Longer-term Vascular Care

    Longer-term aftercare may focus on augmenting the immediate post-treatment emphasis on medical and physical monitoring with longer-term strategies for optimizing your vascular and whole-body health.

    Prior to treatment (if possible), patients seeking to optimize their vascular function may want to work with their physician(s) to craft a long-term aftercare program. Research suggests that the following items may be helpful to those looking to optimize their vascular and whole-body health:

     

     

    Beyond returning to your pre-procedure levels of physical activity (or beyond), many patients have found it helpful to work with specialized MS physical therapists after angioplasty. For example, some patients report renewed energy and/or renewed mobility after treatment. However, because patients may be reacquainting themselves with muscles they haven't used in some while, a physical therapist may be able to help avoid injury or overexertion. Further, a physical therapist can help you craft a new and more vigorous exercise routine commensurate with your physical abilities. Note, however, that you should always plan your exercise regimen in conjunction with your treating physician and, whenever possible, your neurologist.

    That said, we understand that patients with advanced disability may not be able to engage in many types of physical activities. Below, we provide a list of exercises appropriate for those with mild to moderate disability. Following this list we provide options for those with more advanced disability.

    Exercise for those with moderate to light disability:

    Patients with moderate to light disability wishing to expand their exercise routine may consider the following:

     

    Considerations for those with advanced disability:

    In a 2005 literature review of the effects of exercise on MS patient health,10 Herbert I. Karpatkin PT, NCS, notes, "With greater involvement [of disease progression], ability to exercise may become progressively lessened. The ability to engage in aerobic training via a treadmill... may not be feasible. Conventional resistance training may similarly be infeasible... Cognitive impairment may prevent compliance with exercise protocols. However, none of these factors are truly contraindications to exercise—they may represent reasons why exercise may be difficult, but not reasons that exercise should be avoided. Persons with advanced disease may derive benefit from exercise, but they require a program suited to their current capabilities."

    Clearly, those with advanced disability can benefit from exercise. Patients in wheelchairs often benefit from increased arm strength, which can improve mobility, facilitate transitions, and minimize reliance on a caregiver. Moreover, patients with advanced disability who don't get sufficient exercise are at greater risk for chronic issues like obesity, cardiovascular disease, and diabetes.

    However, exercise must be feasible and appropriate for each individual's situation. Thus, we don't recommend any single exercise regiment, but instead suggest that those with more advanced disability work with a physical therapist experienced in MS to craft an individualized, goal-oriented plan that considers your particular strengths and weaknesses, defines your long-term concerns, and creates a pragmatic exercise regimen to help counterbalance your disability and maximize your autonomy.

    In addition to the tips above, which patients may begin immediately to very soon after treatment and continue for years thereafter, patients may want to craft a full-body lifestyle program emphasizing cardio and vascular health. Dr. John Cooke's book "The Cardiovascular Cure" provides an excellent starting point for those interested in understanding their cardiovascular system and how to preserve it. A good primer on Dr. Cooke's approach is available here.

    Notably, CCSVI Alliance's Endothelial Health program builds upon Dr. Cooke's program, emphasizing the following research-based components of vascular health:

    The wide body of research supporting these activities is available in our Endothelial Health Program, which, ideally, should be read in conjunction with the information on this page.

    We hope these activities can serve as a "menu" from which patients, together with their physicians, can craft an individualized, long-term vascular health plan that not only augments any vascular benefits resulting from treatment, but that serves as the foundation for whole-body health. As always, CCSVI Alliance welcomes your This email address is being protected from spambots. You need JavaScript enabled to view it. on our aftercare program.

    Be well!

     

    References

    1. Zamboni P, Galeotti R, Menegatti E, Malagoni AM, Gianesini S, Bartolomei I, Mascoli F, Salvi F. A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency. J Vasc Surg.2009 Dec;50(6):1348-58.e1-3. Erratum in: J Vasc Surg. 2010 Apr;51(4):1079
    2. Ludyga T, Kazibudzki M, Simka M, Hartel M, Swierad M, Piegza J, Latacz P, Sedlak L, Tochowicz M. Endovascular treatment for chronic cerebrospinal venous insufficiency: is the procedure safe? Phlebology. 2010 Dec;25(6):286-95.
    3. Thomas Acold. Dehydration Causes, Symptoms and Treatment - The Health Benefits of Proper Hydration. http://www.suite101.com/content/dehydration-causes-symptoms-and-treatment-a215118. Accessed 6/1/2011.
    4. Yara Dadalti Fragoso, Diego Luiz Ballio Santana, Rodrigo Cruz Pinto The positive effects of a physical activity program for multiple sclerosis patients with fatigue. Neurorehabilitation, 1878-6448 (Online) Volume 23, Number 2 / 2008 Pages153-157.
    5. Motl RW, McAuley E. Association between change in physical activity and short-term disability progression in multiple sclerosis. J Rehabil Med. 2011 Mar;43(4):305-10.
    6. Pilutti LA, Lelli DA, Paulseth JE, Crome M, Jiang S, Rathbone MP, Hicks AL. Effects of 12 weeks of supported treadmill training on functional ability and quality of life in progressive multiple sclerosis: a pilot study. Arch Phys Med Rehabil. 2011 Jan;92(1):31-6.
    7. Suh Y, Motl RW, Mohr DC. Physical activity, disability, and mood in the early stage of multiple sclerosis. Disabil Health J. 2010 Apr;3(2):93-8. Epub 2009 Nov 1.
    8. Gielen S, Sandri M, Erbs S, Adams V. Exercise-induced Modulation of Endothelial Nitric Oxide Production. Curr Pharm Biotechnol. 2011 Jan 11.
    9. Herbert I. Karpatkin PT, NCS, Multiple Sclerosis and Exercise – A Review of The Evidence. Int J MS Care. 2005;7:36-41.
    10. Berger S, Lavie L. Endothelial progenitor cells in cardiovascular disease and hypoxia-potential implications to obstructive sleep apnea. Translational Research. 2011 Jul;158(1):1-13.
    11. Lovato N, Lack L. The effects of napping on cognitive functioning. Prog Brain Res. 2010;185:155-66.
    12. Brass SD, Duquette P, Proulx-Therrien J, Auerbach S. Sleep disorders in patients with multiple sclerosis. Sleep Med Rev. 2010 Apr;14(2):121-9.

     

     

    Last Updated on Thursday, 12 September 2013 19:01